Hepatic, or liver, disease affects more than 100 million people in the U.S. About 4.5 million adults (1.8%) have been diagnosed with liver disease, but it is estimated that between 80 and 100 million adults in the U.S. have undiagnosed fatty liver disease in varying stages. Over time, undiagnosed and untreated hepatic diseases can lead to cirrhosis, a severe scarring of the liver that cannot be reversed.