Children in sub-Saharan Africa have the world’s highest rates of under-5 mortality at 74 deaths per 1,000 live births, which is 14 times higher than the risk for children in North America and Europe. In 2021, sub-Saharan Africa accounted for more than 80% of under-5 mortality worldwide. Sadly, the causes of death, such as diarrhea, malaria and preterm birth, are mostly preventable or treatable.