In an advance for critical care medicine, two international studies published in parallel in the journal Nature Medicine have established a new unified framework for understanding the biological chaos of sepsis and other life-threatening illnesses. A University of Malta researcher, Dr. Brendon Scicluna of the Department of Applied Biomedical Science, Faculty of Health Sciences, designed and spearheaded one of the studies and made significant contributions to the second, placing the University at the forefront of the global effort to bring precision medicine to the sickest patients in our hospitals.